• 24Jan

    Is blood donation safe?

    In adults blood components – red cells, white cells and platelets – are produced and formed in the bone marrow. The protein components of blood are produced in liver. Blood cells and other components are continuously replaced because of their limited life span. Many people are afraid of blood donating for reasons ranging from fear of pain to contracting a dreadful disease. In reality, blood donation is a very safe procedure which is conducted in a well-controlled environment, under the guidance of experienced medical and paramedical personnel. All aseptic precautions are taken to prevent the transmission of any communicable disease and assure the safety of donor.  


    The complete blood donation procedure lasts about an hour, door to door. Though it is considered as a safe procedure, a few potential risks do exist relating to the condition of the donor or the procedure of donation. Most people between the age of 18 and 65 years and in good health condition are able to donate 350 -450 ml of blood.

    Potential risks of blood donation

    • Hypotension - low blood pressure or hypotension may cause donors to feel faint, lightheaded or dizzy during or after the procedure of blood donation. This may be related to dehydration, hunger (resulting in hypoglycemia) and anxiety. To avoid such situation donors should be fresh after eight-hour sleep, eat a well-balanced meal and drink plenty of water before donating blood. Prior to donation potential donors undergo standard examination of their vital parameters (temperature, pulse rate, blood pressure), hydration, anemia and are screened for other illness. If their health condition is not good enough, they are refused to take part in the procedure. After donation donors are usually offered a snack with juice and observed for a short period before leaving.
    • Most people between the age of 18 and 65 years and in good health can donate 350 to 450 ml of blood.

      Most people between the age of 18 and 65 years and in good health can donate 350 to 450 ml of blood.

      Weakness - donors may feel mild weakness after donating blood. It may be only a psychological effect or be due to reduction of red blood cells, though it is a fraction of the total number. Plasma is replaced within 24 hours and red cells in a month time. Donors are instructed to avoid physical exertion for 24 hours after donation, drink plenty of fluids, eat healthy meals and avoid alcohol for a few days.

    • Venipuncture site injury - due to use of large caliber needle for blood collection (to prevent breakdown of red cells), some donors may develop pain or bruising at the needle puncture. Rarely arterial puncture may result in temporary spasm and distal radiating pain. It subsides with a gentle massage and rest. Application of firm pressure for about five minutes after removal of the needle should prevent bruising. Thrombophlebitis (inflammation of the vein resulting in clotting of blood), nerve and tendon damage may occur rarely and may require medical attention.
    • Hypocalcemia - donors of components undergoing apheresis may react to the sodium citrate (anticoagulant added to blood). Sodium citrate binds with the circulating calcium ions in blood, resulting in hypocalcemia (reduced level of calcium in blood). The clinical features of hypocalcemia include tingling in the lips, spasms in hands and feet or generalized convulsions. This can be prevented by providing calcium supplements to the donor.
    • Usage of non-sterilized equipment and needles can increase risk of infection to donors. However, in most cases the sterility of the donation kit is maintained.
    • Though the blood donation is not contraindicated while having menstrual bleeding, it increases the likelihood of developing iron deficiency anemia. This effect can be minimized by taking supplemental iron.
    • The performance of a sportsperson who indulges in high energy sports (football, basketball) may be affected for a brief period, if they develop iron or vitamin B deficiency. They should be advised appropriately about the necessary intake of nutrients to prevent this occurrence. After a strenuous exercise, one should recover completely and hydrate before deciding for donation.

    Blood donation is a completely safe procedure, when conducted after proper screening and under medical supervision. It is essential to have in mind that blood is an important resource though limited and can be used to save lives of people.

    Anna L.

    It’s all about health!
    I have academic background in drugs related Chemical Technology, as well as extensive professional experience in pharma and medical companies. My main area of interest is everyday life medicine. The goal of my articles is to give people informative answers to the questions that bother them, to dispel doubts and some common misbeliefs and also to inspire everyone to keep healthy lifestyle.

    More Posts

Share your thoughts about the article